Fundamental and Industrial Microbiology

SCIENCE BRANCH OF BASIC AND INDUSTRIAL MICROBIOLOGY

 Basic and Industrial Microbiology Science Branch had been established in 2009. Teaching and research activities started in 2010 which still continues at the Faculty of Science.  Prof.Dr. Ece ŞEN has been the chairperson since the establishment of this science branch. There is one professor (Prof.. Dr. Ece ŞEN) an one teaching assistant ( Dr. Deniz AKSOY) in this science branch.

Our Research Areas:

Molecular microbiology, Microbial genetics, Microbial biotechnology, Philogenetic analysis and species identification of microorganisms.

Our Research Subjects:

Molecular epidemiology of newly emerging bacteria (Borrelia sp., Leptospira sp., Anaplasma sp.)

Assesment of environmental carcinogens by using bacteriological  Ames test  

Molecular analysis of bacteria-cancer relationships

Salmonella, their mechanisms of pathogenesis and  molecular identification

Newly emerging pathogens in environmental water sources and their molecular identification

Assesment of efficiency of  new water pollution indicator microorganisms

Development of rapid diagnostic DNA chips

 Microbial insecticides

Tick-borne newly emerging pathogens

Development of biological control methods against ticks.

Our Projects

1. Assesment of mutagens in surface water and drinking water sources by bacteriological Ames test (TÜBAP) (Completed)

2. Establishment of Molecular microbiology and applied molecular microbiology graduate student laboratories (TÜBAP) (Personal investigation project) (Completed)

3. Molecular identification of microbial pollution indicators and newly emerging bacterial pathogens in water sources in Edirne and surroundings (TÜBAP) (Completed)

4. Determinants of pathogenesis of Salmonella spp. strains and their utilization in the molecular identification of salmonelloses (TÜBAP) (YÖK/ÖYP) (Completed)

5. Isolation of tick and field mice born pathogenic spirochetes and  investigation of effects of biological and chemical insecticides on ticks and their transmission of spirochetes (TÜBAP) (Completed)

6. Investigation of hard ticks of  Hyalomma ssp., Rhipicephalus ssp.in Edirne and their in vitro biogenic activities  (Continuing)

7. Antitumorogenic activity of bacteria (Continuing)


Publications (SCI, SCI-EXP):

1.AKSOY DENİZ,ŞEN ECE (2018).  Salmonella enterica Plazmitlerinin Antibiyotik Duyarlılığı ve Caenorhabditis elegans Patojenitesindeki Rollerinin Belirlenmesi.  Mikrobiyoloji Bulteni, 52(1), 80-88., Doi: 10.5578/mb.60767 (Yayın No: 4720389)(SCI-EXP)

2.Aksoy, D.ve  E.Şen. Investigation of Pathogenic Phenotypes and Virulance Determinants of Food-borne Salmonella enterica Strains in Caenorhabditis elegans Animal Model. Microbiol. Bull.2015., 49(4):513-524. (SCI-EXP)

3.KAZAR Gamze,ŞEN ECE (2016).  Investigation of Antitumorigenic Effects of Food Borne Non Pathogenic and Pathogenic Salmonella enterica Strains on MEF  DU145 and HeLa Cell Lines.  Mikrobiyoloji Bulteni, 50(3), 382-391., Doi: 10.5578/mb.26554 (Yayın No: 2841269)(SCI-EXP)

4.Sakakibara Keiko,ŞEN ECE,Sato Kozue,Kawabata Hiroki,Ohashi Norio,Masuzawa Toshiyuki (2016).     Detection and Characterization of the Emerging Relapsing Fever Pathogen  Borrelia miyamotoi       from the  Ixodes ricinus  Tick in  Rural Trakya  Thrace  Region of Northwestern Turkey  .  Vector-Borne and Zoonotic Diseases, 16(12), 797-799., Doi: 10.1089/vbz.2016.2012 (Yayın No: 3330521)(SCI)

MSc and PhD Students:

Graduated students:

Hatice Soylu  (MSc, Dissertation: ’Edirne İlindeki Çevresel Sular ve İçme-Kullanma Sularının Bakteriyolojik Ames Testi ile Mutajenitelerinin Araştırılması) , Müjdat Özgür (MSc, Dissertation: Edirne İlindeki Çevresel Sularda Kirlilik İndikatörü Mikroorganizmaların ve Yeni Çıkan  Bakteriyel Patojenlerin Moleküler Yöntemlerle Saptanması),  Dr. Deniz Aksoy (PhD, Dissertation: Salmonella spp. Kökenlerinin Patogenez Determinantları ve Salmonellozların Moleküler Tanısında Kullanımları)

Continuing students:

Müjdat Özgür (PhD), Gamze Kazar (PhD) , Hatice Soylu (PhD), Büşra Özen (MSc), Süleyman Doğru (MSc)

Our Laboratory Equipment:

Biological safety cabinet, PCR (thermal cycler) (Gradient PCR), horizontal midi gel electrophoresis equipment, power source, incubator, colony counter, Ph meter, microfuge, vortex, water bath, electrical incinerator/sterilizer, PCR sterilization cabinet, immunoblotting transfer equipment, sterile cell culture and biological safety level II isolation room , inverted phase contrast light microscope, dark field microscope and camera/video attachments, carbondioxide incubator, bacteriological incubator, Animal bioassay cages with HEPA filter (Equipment were purchased by TÜBAP grants), 

Courses Offered by Our Science Branch:

Undergraduate courses:

General Microbiology II

General Microbiology II Laboratory

Molecular Evolution

Microbial Ecology

Virology

Introduction to Biotechnology

Introduction to Molecular Microbiology

Graduate Courses:

Water Microbiology

Advanced Molecular Microbiology

Industrial Microbiology

Microbial Technology

Advanced Biotechnology

Applied Microbial Genetics

Faculty Courses:

Biotechnology

Genetically Modified Organisms (GMO)

Faculty of Health Sciences Course:

Molecular Microbiology and Applications