Molecular Microbiology and Biotechnology

Our research group, founded by our retired faculty member Prof. Dr. Ece ŞEN, continues its activities under the leadership of the head of the department, Prof. Dr. Burhan ŞEN, and Dr. Deniz YÜKSEL YENCE (Research Assistant).

Our group focuses on research in the fields of nanotechnology, detection of foodborne pathogens, antibiotic resistance, biofilm formation, molecular identification of fungi, and in vivo antimicrobial activity determination using the Caenorhabditis elegans model system.

Scientific Publications of Our Research Group in the Last 5 Years

Göger G, Şengel SB, Yüksel Yence D, (2025) Preparation of nano(micro)particles from Cotinus coggygria Scop. extracts and investigation of their antimicrobial effects in vivo Caenorhabditis elegans model, Microbial Pathogenesis, https://doi.org/10.1016/j.micpath.2025.107303. (SCI-SCI Exp Q2)

Yavaş, S. T., Yüksel Yence, D. & Şen, E. (2025) Hydrochloric Acid Application Improves the Detection of Salmonella spp. and Escherichia coli O157: H7 in Food Samples. Kirklareli University Journal of Engineering and Science, 11(1), 1-10. (Alan endeksi)

POLAT İ, ŞEN B, KAYNAK ONURDAĞ F (2024). Salmonella enterica serotypes isolated for the first time in laying hens, and their susceptibility to antibiotics. POULTRY SCIENCE, Doi: 10.1016/j.psj.2023.103180. (SCI-SCI Exp Q1)

Göger G, Yüksel D, Göger F, Köse YB, Demirci F. (2024) Antimicrobial evaluation of Tripleurospermum callosum (Boiss. & Heldr.) E. Hossain extracts using in vitro and in vivo Caenorhabditis elegans model against urinary system pathogens. Int J Environ Health Res. 2024 Mar;34(3):1466-1478. doi: 10.1080/09603123.2023.2221641. Epub 2023 Jun 8. PMID: 37288869. (SCI-SCI Exp Q2)

Yüksel, D., Şen, E. (2023) Antibiotic resistance and biofilm forming abilities of Listeria monocytogenes and effect of subMIC concentration of white vinegar on these virulence factors. Acta Alimentaria, An International Journal of Food Science (https://doi.org/10.1556/066.2022.00239) (SCI-SCI Exp Q4)

Aksoy (Yüksel Yence), D. (2021) Microbiological Quality Aspects of Ready to Eat Foods with Focus on Antibiotic Resistance and Biofilm Formation Abilities of Foodborne Bacteria, Acta Alimentaria, An International Journal of Food Science (doi:https://doi.org/10.1556/066.2021.00061) (SCI-SCI Exp Q4)

ÖKTEN S, ŞEN B, KAYNAK ONURDAĞ F, KOLUKIRIK M, ASAN A (2020) Is new generation sequencing an alternative to cultivation based methods for investigating fungal diversity in indoor air samples?. Aerobiologia, 36(3), 433-440., Doi: https://doi.org/10.1007/s10453-020-09642-y (SCI-SCI Exp Q3)

Tikveşli M, ASAN A,GÜRCAN Ş, ŞEN B (2020) Fungal biodiversity on slippers and carpets dusts in three mosques of Edirne City, Turkey (Türkiye’de Edirne şehrinin üç camisinde halı tozları ve terliklerde mantar biyoçeşitliliği).       Mantar Dergisi – The Journal of Fungus, 11(2), 105-113., Doi: 10.30708.mantar.673175 (Alan endeksi)

Scientific Projects of Our Research Group in the Last 5 Years

Biodiversity of Endolichenic Fungi (ELF) Isolated from Similar Host Lichen Lineages Between East Asia and Far West Asia, TÜBİTAK (221N004), International Bilateral Cooperation Programs, Researcher: Burhan Şen, 2022 - Ongoing Project

Polyphasic Taxonomy of Heat-Resistant Paecilomyces and Related Genera Isolates Found in Soil Samples Collected from Various Locations in Different Provinces of Turkey, TÜBİTAK 1001, Project manager: Burhan Şen, 2023 - Ongoing Project (TÜBİTAK 123Z038)

Development of MLSA, MALDI-TOF MS, and FT-IR Databases for Accurate and Rapid Identification of Non-Spore-Forming Molds and Determination of Their Metabolite Profiles, TÜBİTAK 1001, Researcher: Burhan Şen, 2023 - Ongoing Project (TÜBİTAK-122Z256)

Polyphasic Taxonomy of Soil-Borne Heat-Resistant Aspergillus Species in Turkey (118Z359), TÜBİTAK 1001, Researcher: Burhan Şen, 2018 - 2022 (Completed Project 118Z359)

Biological Control of Armillaria spp. and Phytophthora spp. Damage in Oak Trees Using Trichoderma viride - Yumurtatepe Case Study, (Project No: 10.4801/2014-2019/2020), Other Public Institutions (excluding Higher Education Institutions), Researcher: Burhan Şen, 2014-2021 (National - Marmara Forestry Research Institute)

Serotyping of Salmonella Isolates Obtained from Laying Hen Litter in Kırklareli, Edirne, and Tekirdağ Provinces and Determination of Their Sensitivity to Antibiotics, Silver Nanoparticles, and Disinfectants with Different Chemical Structures, Scientific Research Project Supported by Higher Education Institutions (TÜBAP), Project manager Burhan Şen, 2022 - Ongoing

Development of a Multiplex Real-Time PCR-Based Method for the Rapid Detection of Clinically Important Trichophyton Species, Scientific Research Project Supported by Higher Education Institutions (TÜBAP), Project manager: Burhan Şen, 2018 - 2021

Evaluation of the Supernatant Bioactivities of Some Standard Strains of Penicillium and Talaromyces Grown in Modified Media, Scientific Research Project Supported by Higher Education Institutions (TÜBAP), Researcher: Burhan Şen, 26/10/2022 - 2024

Molecular Identification of Aspergillus spp. Isolates from Grapes and Determination of Their Ochratoxin Production Potential, Scientific Research Project Supported by Higher Education Institutions, Researcher: Burhan Şen, FBA-2019-3028, 2019 - 2021

Detection of Staphylococcus aureus in Raw Milk and Traditional Cheeses, Determination of Antibiotic Resistance, Presence of Enterotoxin Genes, and Biofilm Formation Characteristics, Trakya University Research Fund, Project No: 2024/111, Project manager: Deniz Yüksel Yence, 2024 - Ongoing

Preparation of Nano/Micro Particles from Cotinus coggygria Scop. Plant Extracts and Investigation of Their Antimicrobial Effects in the In Vivo Caenorhabditis elegans Model, Trakya University Research Fund, Project manager: Deniz Yüksel Yence, 2021 - 2023

Investigation of the Antimicrobial Effects of Tripleurospermum callosum (Boiss. & Heldr.) E. Hossain Plant Extracts in the In Vivo Caenorhabditis elegans Model, TÜBİTAK-3501, Researcher: Deniz Yüksel Yence, 2019 - 2022

Microbiological Examination of Ready-to-Eat Foods in Edirne Province and Investigation of the Presence, Antibiotic Susceptibility Profiles, and Virulence Factors of Listeria monocytogenes and Staphylococcus aureus in These Foods, Trakya University Research Fund, Project No: 2018/90, Project manager: Deniz Yüksel Yence, 2018 - 2021